Deep Space 4 was a Federation deep space station and starbase near the Typhon Expanse. Around 2372, DS4 became a sector hub for renewed Starfleet interest in the Typhon Expanse region and exploration beyond the Expanse.

Admiral Zahara Hogan was the station's commanding officer and the sector commander in 2372. (Star Trek: The Cantabrian Expeditions: "Catalyst, Part One")

In 2373, the USS Cantabrian underwent repairs at DS4 over the period of several months. (Star Trek: The Cantabrian Expeditions: "Repercussions")

United Federation of Planets starbases
Starbases: 125294Expanse 3Expanse 4Expanse 7Expanse 12Farpoint
Deep space stations: 345912
Deep space stations: Pendragon reality: 99-II

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